Forum consensus is that the Assimil “El catalan sin esfuerzo” is one of the best Assimil courses out there- but you have to know Spanish. I really liked the Assimil method and I’m thinking about buying it to study Catalan. Since I have an equivalent knowledge of both Spanish and. Catalan Sin Esfuerzo by Assimil, , available at Book Depository with free delivery worldwide.

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Ask specific questions about your target languages. Best Courses for Learning Catalan? If this did become a new country, I could see an increased interest in people wishing to study the language.

Catalan Sin Esfuerzo : Assimil :

I tried the online course parla. It has several languages as a base including Spanish, English, German and even just monolingual Catalan.

If I ever decide to learn Catalan, I would include it along with parallel texts. I can learn a lot from just listening, reading and parallel texts. It’s just easier when you know closely related languages.

Last edited by Arnaud on Tue Sep 13, 5: I’ve personally enjoyed the French one more, but that’s more than likely due to the fact that I have a better level in French than in Spanish. The problem is that it is all in Catalan so of little use to a beginner. Assimil if you don’t have any knowledge of Spanish or French there are English-base Colloquial and Teach Yourself courses available for Catalan.

I purchased two of the course manuals along with the accompanying 5 CDs from the now-defunct language course publisher and reseller Audio-Forum the company has been resurrected by new owners; however, they do not currently list courses for Catalan.

You can still find copies of the course books on Amazon and elsewhere: If anyone is truly interested in this course and can locate the course books only, but cannot find a seller of the CDs, I would entertain continued discussions via the Private Message Function. Last edited by Speakeasy on Thu Nov 19, 2: While most of the recommendations for course materials reflect those already mentioned above, some of the discussion threads contained interesting comments on the language itself.

Here is a small selection: Does anyone know any sites for free streaming video for Catalan? I haven’t been able to find much of anything anywhere.

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CIMZIA is indicated for the treatment of adults with moderately to severely active rheumatoid arthritis; CIMZIA is indicated for the treatment of . drug interactions. o Cimzia is indicated for reducing signs and symptoms of Crohn’s disease and modifying anti-rheumatic drug (DMARD). 3. Cimzia [package insert]. Smyrna. Medscape – Rheumatoid arthritis and Crohn disease dosing for Cimzia ( certolizumab pegol), frequency-based adverse effects, comprehensive interactions.

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Cimzia is mostly used for conditions that are severe, moderately severe or getting worse, or when patients cannot use other treatments. For detailed information on the use of Cimzia in all conditions, see the summary of product characteristics.

Cimzia can only be obtained with a prescription and treatment should only be started by a specialist doctor who has experience in diagnosing and treating the diseases that Cimzia is used to treat.

Cimzia | European Medicines Agency

Cimzia is lackage as pre-filled syringes, prefilled pens and dose-dispenser cartridge. It is given by injection under the skin, usually in the thigh or abdomen tummy. Treatment starts with a mg dose given as two injections, followed by a further mg dose two and four weeks later. After this, depending on the condition pafkage treated, patients should continue with mg or mg, given as one or two injections every two or four weeks. After training, patients may inject Cimzia themselves if their doctor agrees.

A monoclonal antibody is a protein that has been designed to recognise and attach to a specific structure in the body.

Dosing Information

Certolizumab pegol has been designed to attach to a messenger protein in the body called tumour necrosis factor alpha TNF-alpha. This messenger is cimziaa in causing inflammation and is found at high levels in patients with the diseases that Cimzia is used for. By blocking TNF-alpha, certolizumab pegol reduces inflammation and other symptoms of the diseases.

Pegylation decreases the rate at which the substance is removed from the body and allows the medicine to be given less often. Nine cimzla studies involving over 3, patients have found Cimzia effective for reducing symptoms of inflammatory conditions.

The studies included adults with active rheumatoid arthritis, axial spondyloarthritis, psoriatic arthritis and moderate to severe plaque psoriasis:. Similar results were seen cimzzia a study with patients who had not adequately responded to other medicines such as methotrexate. However, the dose of Cimzia used in this study was higher than the usual dose. In patients with active rheumatoid arthritis who had never received Packzge, treatment with Cimzia led to sustained remission no detectable disease activity after 52 weeks of treatment.

A third study compared Cimzia with placebo as well as another medicine called etanercept. The most common side effects with Cimzia affecting up to 1 in 10 people are bacterial infections including abscesses cavities containing pusviral infections including herpes, papillomavirus and influenzaeosinophilic disorders disorders of eosinophils, a type of white blood cellleucopenia low white blood cell countsnausea feeling sickheadaches including packaggesensory abnormalities such as numbness, tingling and burning sensationhigh blood pressure, hepatitis liver inflammation including increased levels of liver enzymes, rash, fever, pain, weakness, itching and reactions at the injection site.

For the full ppackage of side effects of Cimzia, see the package leaflet. Cimzia must not be used in patients with active tuberculosis, other severe infections, or moderate to severe heart failure inability of the heart to pump enough blood around the body.

For the full list of restrictions, see the package leaflet. Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Cimzia have been included in the summary of product characteristics and the package leaflet.

As for packags medicines, data on the use of Cimzia are continuously monitored.

Side effects reported with Cimzia are carefully evaluated and any necessary action taken to protect patients. More detail is available in the summary of product characteristics. Cimzia has been shown to reduce the rate of progression of joint damage as measured by X ray and to improve physical function, when given in combination with MTX.

Cimzia is indicated for the treatment of adult patients with severe active axial spondyloarthritis, comprising:. Adults with severe active ankylosing spondylitis who have had an inadequate response to, or are intolerant to nonsteroidal anti-inflammatory drugs NSAIDs.

Cimzia, in combination with MTX, is indicated for the treatment of active psoriatic arthritis in adults when the response to previous DMARD therapy has been inadequate. Cimzia can be given as monotherapy in case of intolerance to methotrexate or when continued treatment with methotrexate is inappropriate.

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Veterinary regulatory Overview Research and development Marketing authorisation Post-authorisation. Table of contents Overview Authorisation details Product information Assessment history. An overview of Cimzia and why it is authorised in the EU Cimzia is a medicine that is used in adults to treat the following diseases: Cimzia contains the active substance certolizumab pegol.

Expand all Collapse all. For more information see the package leaflet or contact your doctor or pharmacist. The studies included adults with active rheumatoid arthritis, axial spondyloarthritis, psoriatic arthritis and moderate to severe plaque psoriasis: For active rheumatoid arthritis that had not improved adequately with disease-modifying antirheumatic drug DMARD treatment, two main studies found Cimzia effective when used with methotrexate when compared with placebo dummy treatment.

Also, X-rays showed that joint damage worsened to a lesser extent in patients who received Cimzia. In the treatment of moderate to severe plaque psoriasis, Cimzia was compared with placebo in two main studies. Treatment with Cimzia mg every two weeks in the two studies led to Patients on Cimzia mg every two weeks led to Cimzia received a marketing authorisation valid throughout the EU on 1 October Product details Name Cimzia. You are therefore advised to be selective about which sections or pages you wish to print.

Rheumatoid arthritis Cimzia, in combination with methotrexate MTXis indicated for: Axial spondyloarthritis Cimzia is indicated for the treatment of adult patients with severe active axial spondyloarthritis, comprising: Ankylosing spondylitis AS Adults with severe active ankylosing spondylitis who have had an inadequate response to, or are intolerant to nonsteroidal anti-inflammatory drugs NSAIDs. Psoriatic arthritis Cimzia, in combination with MTX, is indicated for the treatment of active psoriatic arthritis in adults when the response to previous DMARD therapy has been inadequate.

Changes since initial authorisation of medicine List item. Initial marketing-authorisation documents List item.

How useful was this page? Leave this field blank. International non-proprietary name INN or common name. Anatomical therapeutic chemical ATC code.

Date of issue of marketing authorisation valid throughout the European Union.


2. Contents. MARINE PRODUCT CATALOG All products in this catalog comply with any current Urartian Fortifications in Iran BELGIORNO, M.R., BISCIONE, R. & PECORELLA, P.E. Catalogo degli insediamenti, in Pecorella & Salvini (eds. ). Cycles & Wiggle. Connect. Twitter · Facebook · Instagram. Contact. [email protected] Previous Models. | | | | | | |

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Skip to main content. Log In Sign Up. Zur Adaption altorientalischer Motive im reiternomadischen Kunsthandwerk des 7. The activity and efforts of Dr. Stephan Kroll, produced a comprehensive view of Urartu in Iran which has been modified only marginally by later published and unpublished fieldwork. In the last 30 years very few Urartian fortifications have been added to catalobo already discovered by Thanks to the surveys of Kleiss and Kroll the location and the geographical distribution of Urartian fortifications in Iran are well known and, more importantly, good plans have been made of all of the main fortresses and of the majority of the minor ones.

Therefore Iran is probably the best place to attempt to vtus the geographical distribution of Urartian fortifications and to attempt a ranking of those monuments. This involves not a sub-regional area, as in the studies hitherto carried out Biscione, but a wider region. The basic assumptions of this research are two: The lower cities, sometimes associated with the fortresses, are not relevant for this study.

The ranking criterion used is, as in the articles quoted above, the perimeter of the fortification walls of the single sites, which gives a good estimate of the amount of work invested in the monuments and therefore is a good index of their importance to the Urartians.

Reconstructed or hypothetical walls were calculated only if they were needed to close the perimeter of the attested ones and the lowest possible value was chosen, i. The calculations are based on the various published maps and sketches to scale and the buttresses too were included in the calculation. The Urartian fortifications included in this study were founded over a span from the early eighth to the mid seventh centuries, according to dates based on architecture2 and pottery.

In practice, however, none of them seems to have been abandoned before the end of the Urartian period, and all of them coexisted in the mid catslogo century. Therefore the distribution and ranking presented in this article refer to this period.

Other labour-intensive features could be added to the perimeter of the walls, like footings, staircases and graves dug in the rock and so on, but at present I have not found a precise way of correlating these features to the perimeter of the walls One could measure the amount of man-days needed for these characteristics and for the building of the walls, but these calculations could be rather hypothetical and furthermore the graves could have been dug at private expense, therefore the ranking does not include them.

Monumental architecture was included in the calculation of the perimeter when it was either clearly a cataloho of the fortification system or when it was inherently an important attribute of the site, reflecting its importance. The use of ccatalogo perimeter as a ranking criterion obviates the difficulties evidenced by Zimansky As this study involves only Urartu in Iran the dates proposed by Kleiss on architectural grounds are accepted as paradigmatic.

Catwlogo distribution of the mapped Urartian fortifications in Iran. The star Bastam indicates the only fortress of the first rank; squares mark fortresses of the second rank, circles those of the third rank and triangles those of the fourth and last rank based on Kroll A total of 43 fortifications in Iran were mapped Fig.

A graph of the perimeters Fig.

The rank-size distribution of the Urartian fortifications in Iran. There follows a cluster of five fortresses with perimeters ranging from to m, in decreasing order: Verakhram, the largest site of this level has a perimeter which is approximately one half of that of Bastam. The third rank is formed by 10 small fortresses, with perimeters ranging from Ilan Qara to m Kuh-e Zanbil. This cluster is set apart from the one immediately above by a significant difference in perimeter, m between Qalatgah and Ilan Qara, which is The perimeters of the four ranks match those already determined in previous analyses Biscione Furthermore the two fortresses performed similar functions see p.

Bastam therefore could be outside the hierarchy system, reflecting basically the majesty of the king. In this case the real ranks in Iran should be only three: Such a three-ranks system is definitely present in Iran before the foundation of Bastam. The problem about the real place of Bastam could be resolved with a similar study of another significant region of the Urartian kingdom, Armenia. The distribution of the Urartian fortifications of Iran in four ranks see, however, footnote 4 is analogous to the four or more ranks of the settlement pattern of societies at the state level Biscione As the administration in the Urartian kingdom took place in fortresses they should obviously be distributed into the four or more levels typical of the settlement pattern of state soci- eties e.

Let us now examine closer the four ranks. Bastam, considered a Residenzburg by Kleiss a: It is to be remarked that all the second rank sites according to Zimansky In any case this group of fortresses can also be empirically be singled out thanks to the fact that they control economically important areas. Seqindel, the main site of the Ahar region, carried out the task alone. Sangar is also included by Kleiss in the list of Hauptorte as the main site of the Maku area, but in the end it was probably dependent on Verakhram 5 Oddly enough the valley of Qareh Zia od-Din is smaller than those of Urmia, Khoy and Salmas Zimansky One of the sites, Gerd-e Qisal, is not a real fortification but rather a fortified settlement of a small size.

The above-mentioned functions and the presence of a fortified settlement show clearly that these sites were not relevant for administration purposes. The observed distribution of the fortifications was also checked against the theoretical, log-normal distri- bution8 calculated on the basis of the perimeter of the largest site and the number of fortifications Fig.

Comparison of the observed distribution of the Urartian fortifications in Iran thick line with squares and of the theoretical log-normal distribution thin line with triangles. Duchgagi and Agrab Tepe, are close to the log-normal distribu- tion respectively observed and log-normal ; and Curves with observed perimeters larger than the theoretical log-normal one have also been found in other studies of fortifications Biscione In the case of non-military settlements such a distribution generally means either that the main sites have a low degree of control on the smaller ones, or that two different and interfering systems of control are active 8 The log-normal distribution is represented by a curved line, not by a straight one as in the graphs generally used for non-military settle- ments ranked on the area in hectaresbecause in the present graphs natural and not logarithmic scales are used.

Logarithmic scales are useful with settlements because they show the lowest part of the distributions settlements with a surface between 10 and 1 hectare, i.

As the perimeter of the Urartian fortifications is at minimum metres i. Therefore it was preferred to use a natural scale. These explanations cannot apply to fortifications, because they cannot be of negligible dimensions and must have some degree of administrative and military autonomy in case the chain of command is broken.

Fortifications inherently must have a substantial structure and a significant perimeter and should be larger than the size predicted by the log-normal distribution used for non-military settlements Biscione Furthermore all the sites of each rank are included in this graph Fig. If the curves are drawn with the average perimeters of the fortifications of Ranks 2 to 4 respectively Comparison of the observed distribution of the average perimeter of the Urartian fortifications in Iran of the four ranks thick line with squares and of the theoretical log-normal distribution thin line with triangles.

The observed distribution in this case is primate i. This suggests that in the various hierarchical groups on a vertical line Bastam — fortress of Rank 2 — small fortress of Rank 3 — fort of Rank 4 the sites of one rank had good control over the sites of the one immediately below, the degree of control increasing as the perimeter gets smaller.

The study of the various groups of fortifications can give further information, not based on pure theory but on observation. The group of fortifications dependent on Bastam Fig. Observed thick line with squares and log-normal thin line with triangles distributions of the perimeter of the Urartian fortifications directly depending from Bastam.

The observed distribu- tion Fig. The distribution suggests a strong control of Bastam over the dependent fortifications. In the group Fig.

Observed thick line with squares and log-normal thin line with triangles distributions of vetys perimeter of the Urartian fortifications of the Verakhram group. The interpretation of the data from the group of fortifications around Livar Fig. The distribution of the perimeters is strongly primate Fig. The very concave curve is most probably due to the fact that no small fortress is known from the Livar region.

The observed distribution is close to log-normal xatalogo beyond it Fig. Observed thick line with squares and log-normal thin line with triangles distributions of the perimeter of the Urartian fortifications of the Livar group. The distribution is again very close to the log-normal Fig. The southernmost group of fortifications, under the control of Qalatgah Fig.

VETUS marine diesel engine M – Engines – Engines and around the engines

The rank-size index published in that article does not coincide with the one here presented because of the more precise measurements and because buttresses too were taken into account. The two graphs too do not coincide because the one published in had logarithmic scale, in order to allow the reader to compare it with those of the open settlements.

Observed thick line with squares and log-normal thin line vefus triangles distributions of the perimeter of the Urartian fortifications of the Qalatgah group.

The above graphs suggest that the degree of control of a site over those of lower rank tends to increase as the perimeter of the main site of each group of fortifications increases. In the graph of Fig. Regression line obtained from the values of the rank-size index of the groups of Urartian fortifications in Iran and the perimeter of the main site of each vetks.

The regression line cahalogo the tendency of the rank-size index to decrease with the increase of the main fortification of each group, suggesting that the degree of control of the main sites on the smaller ones augmented with the increase of the perimeter of the main sites.

This is consistent with the graph shown in Fig. On the basis of the perimeter of the fortifications we can therefore suppose that Bastam controlled closely the fortresses of Rank 2 — and even more strongly the fortifications of Ranks 3 and 4 of the Aq Chay and of the Qareh Zia od-Din plain.

Finally small fortresses of Rank 3 controlled forts of Rank 4. Evidently for the Urartian state fortresses of Rank 2 were the key point, therefore their autonomy was smaller than the autonomy of those of the lower vehus. The connection between the central authority and the governed areas was evidently at Rank 2. Data for Urartu in Iran are clear and allow us to put forward hypotheses and interpretations.

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The problem is whether the other regions of the Urartian kingdom are structured as precisely and as clearly as north-western Iran, that is to say whether we can extend to the other regions of Urartu the conclusions drawn so far, as Zimansky pointed out Iran is practically the keystone of our knowledge of archaeology of Urartu, and it is so mainly thanks to the work of Wolfram Kleiss and Stephan Kroll.

The editors have not sought to impose on the authors a single format for citing ancient texts, but have accepted the preferences of the contributors. Corpus dei testi urartei Vols. Queries to the Sun God: Imperial Administrative Records, Part I: For the text see W. Sargons Feldzug gegen Urartu — v.

Urartskie Klinoobraznye Nadpisi [Urartian cuneiform inscrip- tions], Moscow. Urartskie klinoobraznye nadpisi II. Otkrytija i Publikacii gg.


Segundo o Sistema de Classificação Biofarmacêutica (SCB), a dissolução e a . Eles objetivaram verificar a dissolução in vitro da formulação em uma fase. MODELOS FARMACOCINÉTICOSFASE PK FASE BIOFARMACEUTICA FASE PD Dr. Pedro Alva Plasencia MODELOS FARMACOCINÉTICOS. Fase Biofarmaceutica Pertenece al campo de la Química Farmacéutica. Tiene como propósito colocar en forma adecuada el principio activo a disposición del.

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Requisitos a que deben sujetarse los Terceros Autorizados que realicen las pruebas de intercambiabilidad. Requisitos para realizar los estudios de biocomparabilidad. Al margen un sello con el Escudo Nacional, que dice: Grupo de expertos en pruebas de Intercambiabilidad.

Escuela Superior de Medicina. Axis Clinicals Latina, S. Centro de Estudios de Bioequivalencia, A. Criterios y requisitos generales de Intercambiabilidad biodi sponibilidad o biofarmaceutca. Criterios y requisitos para realizar pruebas de intercambiabilidad biodisponibilidad o bioequivalencia en humanos. Criterios y requisitos para los Terceros Autorizados que realicen los estudios de intercambiabilidad.

Concordancia con nor mas internacionales y mexicanas.

Observancia de la Norma. Esta Norma establece los criterios y especificaciones que deben observarse en: Para efectos de esta Norma se entiende por: La cual debe de ser previamente autorizada por la autoridad giofarmaceutica. Los aditivos pueden ser diferentes que los del medicamento de referencia.

Consta de tres partes: Puede fae no estar aislado. Sus requisitos deben especificarse para un cierto periodo o desde un cierto momento de la partida. Criterios y requisitos generales de Intercambiabilidad biodisponibilidad o bioequivalencia. Esto debe establecerse claramente en el protocolo.

Los resultados pueden ser extrapolables para las otras concentraciones, cumpliendo con los siguientes requisitos: La proporcionalidad se determina bajo los siguientes criterios: Determinar las condiciones de temperatura y tiempo entre otros, en las que el compuesto permanezca estable. Biofarmaceutlca cual debe ser realizada por el fabricante del M.


Los responsables de aseguramiento de calidad de ambas unidades deben verificar dicha actividad. Concordancia con normas internacionales y mexicanas. Esta Norma es parcialmente equivalente a los siguientes documentos: Pharmaceutical Research, ; 9 4. Pharmaceutical research, ; 9: Validation of liquid chromatographic and gas chromatographic methods.

Biofwrmaceutica to pharmacokinetics Journal of Chromatography B. A strategy for validation of bioanalytical methods. Journal of Pharmaceutical and Biomedical Analysis, ; J Validation of chromatographic methods in biomedical analysis.

Journal of Chromatography B. Geneva, World Health Organization.

Sistema de Clasificación Biofarmaceútica

WHO draft guideline on marketing authorization requirements. A new statistical procedures for testing equivalence in two-group comparative bioavailability trials. The principles and practice of stat istics in biological research. Statistical Approaches to Establishing Bioequivalence. A comparison of the two one-sided tests buofarmaceutica and the power approach for assessing the equivalence of average bioavailability.

la farmacia veterinaria es la fase farmacéutica de la medici by Edwin Gamez Villalba on Prezi

Response to Kikwood, TBL.: Treatment of bioequivalence data: Proceedings of Bio- International ’89 issues in the evaluation of bioavailability data, Toronto, Canada, October; The design and analysis of comparative blood-level trial. Current concepts in the pharmaceutical sciences, dosage form design biofarmaceutiica bioavailability, Philadelphia: Lea and Febiger, ; Bioavailability and bioequivalence of pharmaceutical formulations.

Biopharmaceutical statistics for drug development. An exact, confidence interval from untransformed data for the ratio of two formulation biofarmsceutica. Tables for an approximate test for outliers in line ar models. Design and Analysis of Bioavailability and Bioequivalence Studies. Guideline on the investigation of bioequivalence. Conduct and Analysis of Comparative Bioavailability Studies.

Guideline on bioanalytical method validation.

Registro del formato de reporte de eventos adversos. Las condiciones antes mencionadas deben estar establecidos previamente faee el protocolo y quedar descritas en el formato de reporte de caso y en el documento fuente.

Error experimental, denominado variabilidad intrasujeto o residual intrasujeto. Anexar formato y las instrucciones para su llenado.


All about The Lost Letters of Brother Gabriel by Bree Despain. LibraryThing is a cataloging and social networking site for booklovers. The Lost Letters of Brother Gabriel (a Dark Divine Original) by Bree Despain, , available at Book Depository with free delivery. The Lost Letters of Brother Gabriel (A Dark Divine Original) – Ebook written by Bree Despain. Read this book using Google Play Books app on your PC, android .

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Daniel is an Urbat—a werewolf—a Hound of Heaven. Originally angels blessed with power to fight evil, they succumbed to that power and became cursed. Daniel is constantly urging Grace to hold back, however, and the beast inside craves to be set free.

Eventually, Grace meets Talbot, loxt hottie Urbat who embraces his darker side and eggs Grace on to do the same. Meanwhile, Jude has taken up with a wild bunch of Urbats who feel the quickest path to dominating mankind is by knocking over convenient stores. Most of the characters of gavriel first book return for this one, some in diminished roles and some enhanced.

Each minor character affects Grace during their turn on stage, so none were superfluous.

Read The Lost Letters of Brother Gabriel read free novels online by Bree Despain | Full Books

Talbot is the character that has the greatest influence, both as a romantic lead and as a teacher, but not always habriel the best. Gabriel, the ancient Urbat, has his influence as well. Mostly, however, Grace searches to know herself and the role her powers play in her life.

Her struggles to balance her old self with her new self while also trying to maintain the relationships around her is poignant.

The Lost Letters of Brother Gabriel

Also interesting is the history of the Urbats as Grace uncovers secret after secret. If there was one minor flaw in the book, it would be the lack of communication as a plot device.

Daniel and Grace drift apart because of secrets. Breakdowns in communication are the irreconcilable differences that divorce papers are filled with world wide, but sometimes this story felt as if the breakdown was convenient broother give the story more pages. Regardless, it was a minor point and could be testimony to how impatient I was for them to reconcile those differences—evidence that Despain writes believable characters.

Despain has done a great job on world building. There is depth to the story here gabrkel is missing from most books in this genre.

The Lost Saint by Bree Despain – book review

The Lost Saint was an enjoyable tale with strong characters and a deep storyline. Skip to content Search for: Avatars by Sterling Adventures. Sorry, your blog cannot share posts by email.


AML – Technical Manual: AMEK M AMEK M Technical Manual (Copy). Available until stocks are exhausted. £ each () Quantity. Tag: Amek M console. About. About 45+ years of fun and games Paul Christensen and his wife Donna founded Omega Productions in March of Console. Vintage AMEK M, In-Line 40 Channel ls Stereo, 4-Band Full Parametric EQ, Hi/Low Pass Filters.

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Hi I’ve opportunity to buy an Amek m in very great shape There are direct out on all channells?

Those desks were made on special order, so you got what you ordered. Otherwise it might turn into a nightmare to figure out what others changed in circuits and signal flow. December 26, The desk is entirely based on the VCA concept. The master fader is VCA as well. You get great preamps, the best EQ ever and a lot of features with distinctive sound. Not shabby either, but these can be changed to modern That if you want less mud and distortion.

Thanks for great info! Next weeks i will pick up the console and i want to recap and check all, Some advice? Some upgrade or change? Check it out first before you think about upgrades. Recap it of course. The rectifiers are bolted to the bottom of the case.

They can get lose, reducing the thermal coupling to the case. Hence they get baked and are prone to failure. Renew all thermal grease at the all rectifiers, regulators and power transistors.

Audio Maintenance Limited AML – Technical Manual: AMEK M

The TO3 sockets of the regulators and power transistors sometimes have contact problems. Renew these or solder the amke directly, omitting the sockets. After all that you should get ameek of all tantalum caps on the channel strips, which are across the power rails. They sit close to the fader in the logic section. Hi The console is at home!!! The man says me that the console was recapped inbut inside, I see some caps that amk me are the originals The great thing is that there’s a board diary with all the maintenance over the years There are also, very big images with all the schematics!

Now I will try to scan them and if someone need them I will be very happy to share Thanks Jensenmann for all the info These are the original caps. My schematisc are old, very used, barely readable and have a lot of handdrawn “modifications” on it.

Hi I’m starting to compile the buy list for the recapping and Amekk need some help Some say that tantalum caps have infinite life.

Some advice about other caps?

Spectral Recording Studio

The console have j2500 installed the man say Optifile Tetra but I don’t have a original external computer. It’s possible to find something that could work? If not it’s better to remove the automation system? I will receive the schematics scans in the next two days, after that I will share My desk is a pre series version without automation.

Anything from 10uF to uF is fine. Bypasscaps are fine, too, no matter if ceramic or poly.

But never use ceramic bypasscaps on caps in the audiopath. Some tantalums in this desk are in the audiosignalpath. If you want to stick with the original sound then replace with the same cap.

If you want it to sound more clean and modern then replace these caps with electrolytics und increase the capacity value by 2x to 4x.

Tag: Amek M2500 console

Replacing the big PSU caps with something else will be a mechanical problem. Definitely recap the regulator boards and get rid of the tantalums over there. Your copies are on the way.

I’ve also a new spare cap uf, could use it for uf on psu?


copyright issues, please report us to resolve them. We are always happy to assist you. Document Description. Hipotiroid. Document Share . askep hipotiroid. Pathway Hipotiroid ini adalah laporan pendahuluan hipotiroid yang sudah kami buat dengan hati yang ikhlas dan ASKEP HIPOTIROID Patfis HIPOTIROID BAB I KTI hipotiroid Hipotiroid kongenital (odie).docx Hipertiroid Dan Hipotiroid hipotiroid hipotiroid.

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Kami berharap bahwa Anda menikmati presentasi akep. Untuk men-downloadsilahkan rekomendasi presentasi ini kepada teman-teman Anda dalam jaringan sosial. Tombol yang haris diklik terletak di bawah posting ini. Diterbitkan oleh Ridwan Hermawan Telah diubah “3 tahun yang lalu.

Kadar TSHs yang rendah menunjukkan hipertiroid. Suppressed except when etiology is a TSH-secreting pituitary tumor or pituitary resistant to thyroid hormone. Does not respond to thyrotropin-releasing hormone TRH. Elevated related to adrenal involvement.

Low levels less adrenal reserve. Alkaline phosphatase and serum calcium: Hyponatremia may reflect adrenal response or dilutional effect in fluid replacement therapy.

Hypokalemia occurs because of GI losses and diuresis. Atrial fibrillations; shorter systole time; cardiomegaly, heart enlarged with fibrosis and necrosis late signs or in elderly with masked hyperthyroidism. Needle or open biopsy: May be done to determine cause of hyperthyroidism, differentiate cysts or tumors, diagnose enlargement of thyroid gland. Pasien berumur 35 tahun atau lebih Hipertiroidisme yang kambuh sesudah operasi Gagal mencapai remisi sesudah pemberian obat anti tiroid Tidak mampu atau tidak mau pengobatan dengan obat anti tiroid Efek samping: Kekambuhan setelah terapi yang adekuat Hypertiroid yang hebat dengan kelenjar tiroid sangat besar Hypertiroid yang sulit dikontrol Tindakan: Bilateral tiroidectomy atau near total thyroidectomy dan total thyroidectomy Tyrax tiroksin sebagai terapi substitusi Terapi diet Diet harus tinggi kalori; protein; multivitamin serta mineral.

HIPOTIROID | Documents

Imsomnia, sensitivitas meningkat, otot lemah, gangguan koordinasi, Kelelahan berat. Sirkulasi kolaps, syok krisis tirotoksikosis. Discharge Goals Homeostasis achieved.

Patient effectively dealing with current situation. Plan in place to meet needs after discharge. Note widened pulse pressure. Widened pulse pressure reflects compensatory increase in stroke volume and decreased systemic vascular resistance SVR. Monitor central venous pressure CVPif available.

Provides more direct measure of circulating volume and cardiac function. Provides a more accurate assessment of tachycardia. Auscultate heart sounds, noting extra heart sounds, development of gallops and systolic murmurs. Auscultate breath sounds, noting adventitious sounds e. Early sign of pulmonary congestion, reflecting developing cardiac failure.

Rapid dehydration can occur, which reduces circulating volume and compromises cardiac output. Note urine specific gravity. Significant fluid losses through vomiting, diarrhea, diuresis, diaphoresis can lead to profound dehydration, concentrated urine, and weight loss. Observe for adverse side effects of adrenergic antagonists, e. Administer IV fluids as indicated. In the presence of thyrotoxic paralysis primarily occurring in Asian menclose monitoring and cautious replacement are indicated because rebound hyperkalemia can occur as condition abates releasing potassium from the cells.


Elevation may alter cardiac contractility. Pulmonary infection is most frequent precipitating factor of crisis. May demonstrate effects of electrolyte imbalance or ischemic changes reflecting inadequate myocardial oxygen supply in presence of increased metabolic demands.

Cardiac enlargement may occur in response to increased circulatory demands. Pulmonary congestion may be hipktiroid with cardiac decompensation. Provide hypothermia hipotirroid as indicated. Display improved ability to participate in desired activities.

Note development of tachypnea, dyspnea, pallor, and cyanosis. Provide for quiet environment; cool room, decreased sensory stimuli, soothing colors, quiet music.

Reduces stimuli that may aggravate agitation, hyperactivity, and insomnia. Encourage patient to restrict activity and rest in bed as much as possible. Helps counteract effects of increased metabolism. Provide comfort measures, e. May decrease nervous energy, hipotiroie relaxation. Provide for diversional activities that are calming, e. Allows for use of nervous energy in a constructive manner and may reduce anxiety.

Avoid topics that irritate or upset patient. Discuss ways to respond to these feelings.

Increased irritability of the CNS may cause patient to be easily excited, agitated, and prone to emotional outbursts. Discuss with SO reasons for fatigue and emotional lability. Understanding that the behavior is physically based may enhance coping with current situation and encourage SO to respond positively and provide support hipotioid patient. Administer medications as indicated: Combats nervousness, hyperactivity, and insomnia.

Maintain usual reality orientation. May be hypervigilant, restless, extremely sensitive, or crying or may develop frank psychosis. Assess level of anxiety.

Anxiety may alter thought processes. Provide quiet environment; hilotiroid stimuli, cool room, dim lights. Present reality concisely and briefly without challenging illogical thinking. Promotes continual orientation cues to assist patient in maintaining sense of normalcy.

Provide support as needed. Aids in maintaining socialization and orientation. Provide safety hipotirojd, e. Administer medication as indicated, e. Weigh daily and report losses. Continued weight loss in face of adequate caloric intake may indicate failure of antithyroid therapy.

Encourage patient to eat and increase number of meals and snacks, using high-calorie foods that are easily digested. Aids in keeping caloric intake high enough to keep up with rapid expenditure of calories caused by hypermetabolic state. Avoid foods that increase peristalsis e.

Increased motility of GI tract may result in diarrhea and impair absorption of needed nutrients. Consult with dietitian to provide diet high in calories, protein, carbohydrates, and vitamins. May need assistance to ensure adequate intake of nutrients, identify appropriate supplements.

Glucose, vitamin B complex;Insulin small doses. Given to meet energy requirements and prevent or correct hypoglycemia. Aids in controlling serum glucose if elevated.


Anxiety May be related to Physiological factors: Report anxiety reduced to a manageable level. Identify healthy ways to deal with feelings. Mild anxiety may be displayed by irritability and insomnia.

Monitor physical responses, noting palpitations, repetitive movements, hyperventilation, insomnia. Stay with patient, maintaining calm manner. Speak in brief statements, using simple words.

Attention span may be shortened, concentration reduced, limiting ability to hipotiroix information. Place in quiet room; aslep soft, soothing music; reduce bright lights; reduce number of persons contacting patient. Reinforce expectation that emotional control should return as drug therapy progresses.

Provides information and reassures patient that the situation is temporary and will improve with treatment.

Administer antianxiety agents or sedatives and monitor effects. Refer to support systems as needed, e. May be used in conjuction with medical hioptiroid to reduce effects of hyperthyroid secretion. Identify measures to provide protection for eyes and prevent complications.

Elevate the head of the bed and restrict salt intake if indicated. Decreases tissue edema when appropriate, e.


Results 1 – 30 of 30 ADIÓS A LA RAZÓN by FEYERABEND, Paul and a great selection of related books, art and collectibles available now at Adios a la Razon (Filosofia) by Paul Feyerabend at – ISBN – ISBN – Tecnos – – Softcover. Available now at – ISBN: – Soft cover – Tecnos – – Book Condition: New.

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Farewell to Reason by Paul Karl Feyerabend. For all their variety in theme and occasion, the essays in this book share a consistent philosophical purpose. The appeal to reason, he insists, is empty, and must be replaced by a notion of science that subordinates it to the needs of citizens and communities.

Paperbackpages. Published January 17th by Verso first published To see what your friends thought of this book, please sign up. To ask other readers questions about Farewell to Reasonplease sign up.

Farewell to Reason

Lists with This Book. This book is not yet featured on Listopia. Aug 30, Kevin K rated it really liked it Shelves: This is a hard book for me to rate. On the one hand, when I first read parts of Farewell to Reason in the late ’90s, I was electrified by it. It opened my mind to a whole new way of looking at the world Feyerabend’s relativism which I have subscribed to ever since. Unfortunately, the reader of This is a hard book for me to rate. Unfortunately, the reader of FTR has no idea what the original critics actually said.

So it’s a little like coming into a conversation halfway through, where you don’t have most of the background. Much of the book suffers from this type of thoughtlessness toward the reader, and large sections on the philosophy of science are both very dated and incomprehensible. Nevertheless, the first and last essays of FTR rate five stars in my opinion. Among today’s armies of moral crusaders, it’s hard to find a genuine defender of relativism, and Feyerabend is one of the best.

It’s the idea that there is no moral truth, and that “objectivity,” “rationality” and “progress” are phony constructs used primarily by Western people to undermine and destroy the diverse cultures and ways of life which existed in the pre-rational era or remain pre-rational today. Feyerabend’s program perhaps it would be better to call it an “anti-program” is to allow total pluralism and self-determination where all sorts of societies and belief systems are allowed to flourish — without being browbeaten by intellectual elites, and forced into “rational” straight-jackets like free trade, growth economics, secular humanism, liberalism, Marxism etc.

Feyerabend doesn’t hesitate to take on the hard cases either. At one point in FTR he defends the Catholic inquisition as being rational within its own terms, and its arguments as impossible to refute based on any “objective” arguments. A less dramatic, but similar case would be the controversy in recent years over teaching evolution in public schools. Feyerabend’s point of view is that what matters is not the “truth,” but quality of life, and the right of human beings to live in ways they find meaningful and satisfying.

That is, there is nothing wrong with a community of people deciding, through democratic principles, that they want to live a Biblically structured life, and teach their children Creationism.

Of course, this is where the modern inquisition, and the Popes of Objectivity, step in and assert their right to force their “objective” views onto other people’s children. And in today’s America that seems perfectly normal. But translate this behavior to a society more fashionable than evangelical Christians like, say, Indios living in the Amazon.

Do we really need to force their children into schools to learn evolution and other irrelevant garbage that, essentially, is just another missionary White man’s religion to be rammed down their throats like Christianity? As Feyerabend eloquently puts it, “The pygmies, for example, or the Mindoro of the Philippines, do not want equal rights — they just want to be left alone. Gould often said that there is no progress in evolution, and that no species is superior to any other. Species are simply adapted in various degrees to their environment.

Feyerabend deploys similar arguments in the field of human culture.

Essentially, his point is that no culture is superior to any other, and thus there is no reason for one culture to impose its views or ways of life on another. Yes, we could send the Indio children to school, and teach them evolution — instead of the silly, primitive, religious beliefs which dog their parents — along with all the other trappings of our modern “objective” civilization. Their society is already superbly adapted to their environment, and meets their spiritual needs.

Whereas our supposedly advanced society is destroying our environment, and not meeting our spiritual needs! Farewell to Reason has some brilliant, life-changing material in it well, at least it had a big impact on my life and thinkingand is well worth reading — just don’t be hesitant to skim over the chaff. Jul 20, Simon Mcleish rated it really liked it.

Originally published on my blog here in May Farewell to Reason is a collection of essays on the subject of relativism. Though they were rewritten for inclusion in this volume, their independent origin still shows in a certain repetitiveness and in disparity of content – some are far more concentrated on a single theme than others for example, some are criticisms of particular writers.

The essays pick on the same kinds of targets as Feyerabend’s book Against Methodand attack the idea that Originally published on my blog here in May The essays pick on the same kinds of targets as Feyerabend’s book Against Methodand attack the idea that science is a unified whole, with a single overriding method.

Karl Popper is singled out for criticism, but much of what is said would apply to anyone who contrasts “scientific thinking” with other modes of thought this is usually done do dismiss religious ideas. Most of the criticisms that can be made of Against Method are also appropriate here.

The rhetorical style of Feyerabend’s argument, his use of Galileo as a paradigm of scientific method, and the use of counter examples from areas not always regarded as scientific such as economics are faults common to both. The essay form adds new problems, and some parts do not fit into the whole terribly well notably the discussion of Aristotle’s philosophy of mathematics, though it is interesting in itself.

Neither Popper nor Feyerabend seem terribly convincing to me; while it is obvious that not all scientific thought is uniform, most practising scientists have quite similar ideas about what they are trying to do. These differ in details such as the precise relationship between theory, experiment and whatever may count as underlying realitybut then philosophy does not interest many and certainly there are few who would let it affect their work.

The most interesting new point is part of the essay on Galileo and the church, in which Feyerabend parallels the attitude of Catholic cardinals then and the scientific establishment today. As the money and administrative side of scientific research grow every larger, it is more and more difficult to be a successful, rather than starving iconoclast.

For science to have a religious orthodoxy of this kind is a bad thing, and we need people like Feyerabend to continually attack its genesis. Indeed, this could never be achieved, since all we born in a cultural-biased world vision; in fact, he is trying to make his point, without considering others and obliterating the very culture path he eventually was trying to stand up for.

So, at least, his very disrespectful remarks to all universities are, at best, very disgraceful, due to the fact that the contemporary world would need to conciliate his views, not within a rational system closed upon itself, but rather with critical thought. Dec 11, Fatih A.

Farewell to Reason by Paul Karl Feyerabend

May 30, Rui Coelho rated it liked it. More political, but also less bright, than Against the Method. Ryan Haczynski rated it liked it Jan 14, William rated it really liked it Sep 25, Daniel Guzman rated it really liked it Sep 15, Paolo Sala rated it it was amazing Feb 24, Zyxtmurf rated it really liked it Jul 23, Dana Jalobeanu rated it it was amazing Dec 28, Trip rated it really liked it Jun 02, Roy rated it liked it Sep 09, Audrey rated it liked it Jul 14, Dolamroth rated it liked it Jan 18, Sema rated it really liked it Dec 15, Phil rated it it was amazing Jun 23, Peter rated it really liked it Dec 31, Mike Rot rated it really liked it Aug 04, Sam rated it liked it Feb 21, Alex rated it really liked it Oct 02, Lukas Szrot rated it it was amazing Jun 16, Vidar rated it really liked it Aug 04, There are no discussion topics on this book yet.

About Paul Karl Feyerabend. Paul Karl Feyerabend was an Austrian-born philosopher of science best known for his work as a professor of philosophy at the University of California, Berkeley, where he worked for three decades — His major works include Against Method publis Paul Karl Feyerabend was an Austrian-born philosopher of science best known for his work as a professor of philosophy at the University of California, Berkeley, where he worked for three decades — His major works include Against Method published inScience in a Free Society published in and Farewell to Reason a collection of papers published in Feyerabend became famous for his purportedly anarchistic view of science and his rejection of the existence of universal methodological rules.

He is an influential figure in the philosophy of science, and also in the sociology of scientific knowledge. Books by Paul Karl Feyerabend. Trivia About Farewell to Reason. No trivia or quizzes yet. Quotes from Farewell to Reason. Just a moment while we sign you in to your Goodreads account.


CDBCN datasheet, CDBCN pdf, CDBCN data sheet, datasheet, data sheet, pdf, Fairchild Semiconductor, Quad 2-Input NAND Buffered B Series. CDBCN from Texas Instruments High-Performance Analog. Find the PDF Datasheet, Specifications and Distributor Information. CDBCN datasheet, CDBCN circuit, CDBCN data sheet: NSC – Quad 2-Input NOR,NAND Buffered B Series Gate,alldatasheet, datasheet.

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CDBCN Datasheet

They have equal source and sink current capabilities and conform to standard B series output drive. The devices also have buffered outputs which improve transfer characteristics by providing very high gain. All inputs are protected against static discharge with diodes to Vdd and Vss.

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CDBCN (FAIRCHILD) PDF技术资料下载 CDBCN 供应信息 IC Datasheet 数据表 (3/9 页)

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