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TransFect Protocol Database. and two new DNA transfection reagents: Attractene Transfection Reagent and NanoFect Transfection Reagent. I tried Lipofectamine and Attractene which both had a bad efficiency. plate format to do your experiment, the transfection protocol will be DNA/well. 年7月29日 QIAGEN Supplementary Protocol Protocol: Fast?Forward Transfection of cells with DNA using Attractene Transfection Reagent This.

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Routing Protocol vs Ro Forward Transfection of cells with DNA using Attractene Transfection Reagent This protocol uses standard parameters and might require further optimization for transfection with this cell type. The amounts given are ptotocol one well of a 6-well plate. In this protocol, cell plating and transfection are performed on the same day. Shortly before transfection, seed 3x cells per well of a 6-well plate in ?

Cell strategies for high transfection efficiency | Laboratory Talk

Cells may alternatively be seeded after step 3 of this protocol. The amount of transfection reagent and DNA required for optimal performance may vary, depending on the cell line and gene target.

Incubate the samples for 10? Add the complexes drop?

Gently swirl the plate to ensure uniform distribution of the transfection complexes. Incubate the cells with the transfection complexes under their normal growth conditions and monitor gene expression after an appropriate attracteen e. Change the medium as required. The optimal incubation time for gene expression analysis depends on the cell type, the gene expressed, and the method of analysis.

This can be determined by performing a time? For stable transfections, passage cells into the appropriate selection medium 24? Maintain cells in selective culture medium until colonies appear. For this prottocol, further optimization is recommended to achieve maximum transfection efficiency.

As a general rule, optimization of transfection can be performed by varying DNA and Attractene Reagent amount as follows: Use the reagent and nucleic acid amounts listed in the protocol.

Cell strategies for high transfection efficiency

The table below shows a pipetting scheme with 5 different conditions we recommend to test when optimizing transfection i. As a starting point, we recommend using 6-well plate?

The effect of using greater or lesser amounts of DNA and Attractene Transfection Reagent can be observed using these combinations. The Fast-Forward Protocol, in which cell plating and transfection are performed on the same day, attracttene been shown to work successfully with a wide variety of cell types. However, for some cell types, especially difficult-to-transfect cells such as suspension cells and primary cells, higher transfection efficiencies may be achieved by plating cells 24 hours prior to transfection for a atttactene, consult the Attractene Transfection Reagent Handbook at www.

Transfection optimization Optimizing DNA 0.


Using other software freely available on Internet, you can easily convert DVI and PDF to other document formats. In particular, you can obtain the PostScript. It probably came with your TeX distribution. Try this at the command line: dvipdfm This should create a file called NAME. dvipdf – Convert TeX DVI file to PDF using ghostscript and dvips. SYNOPSIS. dvipdf [ options ] [ ] DESCRIPTION. This script invokes.

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In particular, you can obtain the PostScript version using software which is included in your LaTeX distribution. It doesn’t seem logical to create a file with two steps when you can create it straight away, but some users might need it because, as you remember from the first chapters, the format you can generate depends upon the formats of the images you want to include EPS for DVI, PNG and JPG for PDF.

Here you will find sections about different formats with description about how to get it. However, these documents are produced from software that parses and interprets the LaTeX files, and do not implement all the features available for the primary DVI and PDF outputs.

Nonetheless, they do work, and can be crucial tools for collaboration with colleagues who do not edit documents with LaTeX. This chapter features a lot of third-party tools; most of them are installed independently of your TeX distribution. If you have the choice, it is often easier with Unix systems for command line tools.

Some tools may already be installed.

For convertie, you can check if dvipng is installed and ready to use Unix only:. This section describes how to generate a screenshot of a LaTeX page or of a specific part of the page using the LaTeX package preview. Screenshots are useful, for example, if you want to include a LaTeX generated formula on a presentation using you favorite slideware like Powerpoint, Keynote or LibreOffice Impress.

First, start by making sure you have preview.

See Installing Extra Packages. Write this formula in the preview environment:. Note the active option in the package declaration and the preview environment around the equation’s code.

Without any of these two, you won’t get any output. This package is also very useful to export specific parts to other format, or to produce graphics e. Dvvi can also automate the previewing of specific environments:.

This will produce a PDF containing only the listing content, the page layout will depend on the shape of the source code.

If you have created different PDF documents and you want to merge them into one single PDF file you can use the following command-line command. You need to have Ghostscript installed:.

Convert to dvd Video Files Online

Alternatively, PDF-Shuffler is a small python-gtk application, which helps the user to merge or split pdf documents and rotate, crop and rearrange their pages using an interactive and intuitive graphical interface. This program may be available in your Linux distribution’s repository. Another option to check out is pdftk or PDF toolkitwhich is a command-line tool that can manipulate PDFs in many ways.

To merge one or more files, use:. If you are merging external PDF documents into a LaTeX document which is compiled with pdflatexa much simpler option is to use the pdfpages package, e.

Three simple shell scripts using the pdfpages package are provided in the pdfjam bundle by D. They include options to merge several pdf files pdfjoinput several pages in one physical sheet pdfnup and rotate pages pdf See also Modular Documents. See its Wikipedia entry for more details. This conversion is done through latex2rtfwhich may run on any computer platform, however is only actively supported on Windows, Linux and BSD, with the last mac update being from a recent version for OSX is available via MacPorts.

As well, it has some limited support for packages, such as varioref, and natbib. However, many other packages are not supported. The Windows version has a GUI l2rshell. The command-line version is offered for all platforms, and can be used on an example mypaper. Both latex and if needed bibtex commands need to be run before latex2rtfbecause the.

The result of this conversion will create myfile. There are many converters to HTML. Some of them use an intermediate file which then will be converted to the destination format.

Some introductions of pdf2htmlEX can be found on its own wiki page. More technical details can be found on the paper published on TUGboat: TeX4ht has many options and possible configurations, but for a basic conversion. An introduction by the original author was published in TUGboat [1]. So vector graphics are usually preferred. There is still some cases where raster graphics are used:. So SVG is great for drawings and a small amount of text. This however will not generally have sufficient resolution for whole pages or large areas.

Open your file with GIMP. It will ask you which page you want to convert, whether you want to use anti-aliasing choose strong if you want to get something similar to what you see on the screen. Try different resolutions to fit your needs, but dpi should be enough. A method for DVI files is dvipng. Usage is the same as dvipdfm. Run latex as usual to generate the dvi file. Now, we want an X font size formula, where X is measure in pixels. You need to convert this, to dots per inch dpi.

This value will be dvu to dvipng using the flag -D. To generate the desired png file run the command as follows:. The flag -T sets the size of the image. The option tight will only include all ink put on the page.

The option -o sends the output to the file name foo. You can optimize the resulting image using optipng so that it will take up less space. If you are thinking of converting to plain text for dvvi or to count words, there may be an easier way — read Tips and Tricks first. It can handle multi-file projects, so all you need is to give one command:.

LaTeX/Export To Other Formats – Wikibooks, open books for an open world

This will output result to standard output. If you want the plain text go to a file, use. If the output from detex does not satisfy you, you can try a newer version available on Google Codeor convertide HTML conversion first and then copy text from your browser. If you want to keep the formating, you can use a DVI-to-plain text converter, like catdvi. From Wikibooks, open books for an coonvertire world.

Retrieved from ” https: Views Read Edit View history. Policies and guidelines Contact us. This page was last edited on 12 Augustat By using this site, you agree to the Terms of Use and Privacy Policy.


in the Ottoman empire in the years between // in his well- known autonomy from the Ottoman empire initially under the Treaty of Kk Kaynarca (), stanbul, Bulgaristan-Trkiye Antlamas. Ancak Kk Kaynarca Antlamasnda, ilk kez uluslar aras bir ister karlkl antlama saylsn, taraflardan birinin hayat men-faatlerine aykr.

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Published on Dec View Download 2. Baro Han Beyolu – stanbul Tel.: Eminta Kazm Dinol San. Mart Bu kitap, stanbul Barosu Ynetim Kurulunun kararyla adet baslmtr.

Gemi dnemi sonlandryoruz ve yeni bir sayfa ayoruz. Dnemine bir hukuku olarak adn vermi mk Mahmut Esat Bozkurt, btn saygnlyla 79 yl boyunca hkmranl-n srdrd. Bu lkede byk bir disiplin yaratt, imdi yeni bir dnem, uygar dnyaya alm ad altnda balyor. Tam 50 gn sonra 1 Nisan tarihinde yeni bir k yaklacak. Bu k pratikte sizlerin kaynaeca koyaca stn gayretlerle artacak “.

Cumhurbakan Sezer’in Mahmut Esat Bozkurt’un yazd Medeni Yasa’nn gerekelerinin gnmze k tuttu-una iaret ettii belirtilmi; onun: Bu gn daha ok zgrlk istenebiliyorsa, Cumhuriyetin kurulu felsefe-siyle rten almlar tartlabiliyorsa, bunun Atatrk dev-rimlerinin salad zgrlk ortam sayesinde yaplabil-dii unutulmamaldr”.

Topu topu sayfadan oluan Mahmut Esat’n gerekesinin yarsndan ou karlp atl-m, Trk devriminin gerekesi kua benzetilmitir. Bundan be yl nce tasary hazrlamakta olan komisyona zama-nn Adalet Bakan tarafndan 11774 gerekesindeki dinle il-gili ksmlarn karlmas” buyruunun verildiini bilmeyen yoktur Trk devriminin aydnln bir trl anlamayan ve anlamak istemeyen bu arpk dnceliler, ne yazk ki bu kadarla da yetinmeyerek Meclis krssnden ‘geri zekl’ ve ‘aalk’ deyimlerini de kullanmaktan ekinmemilerdir Hali hazrda Trkiye Cumhuriyetinin mdevven bir Kanunu Medenisi yoktur.

Yalnz, akitlerin kk bir ksmna temas ede-bilen Mecelle vardr. Denilebilir ki; bu ka-nunun ihtiyac hazraya tevafuk eden uyan ancak mad-desidir. Mtebakisi memleketimizin ihtiyacn ifade edemiyecek kadar iptidai bir takm kaidelerden ibaret olduundan tatbik edilmemektedir.

Mecellenin antlamws ve ana hatlar, dindir. Hal-buki, hayat beer, hergn hatt her n esasl tahavvllere ma-ruzdur. Bunun tahavvllerini, yryn hi bir zaman bir nokta tarafndan tesbit etmek ve durdurmak mmkn deildir. Kanunlar dine mstenit olan devletler ksa kaynwrca zaman sonra memleketin ve milletin mutalebelerini tatmin edemezler.

Hayat yrr; ihtiyacat sr’atle deiir, din kanunlar, mutlaka ilerle-yen hayatn huzurunda ekilden ve l antlama fazla bir kymet, bir man ifade edemezler.


Deimemek, dinler iin bir zarurettir. Esaslarn dinden alan kanunlar tatbik edil-mekte olduklar camialar nazil olduklar indikleri iptidai de-virlere balarlar ve terakkiyata ilerlemeye mni belli bal kkaynarca ve miller srasnda bulunurlar. Trk milletinin mukadderatn asr hzr iinde dahi Kurunu Vusta orta a ahkm ve kavaidine raptetmekte, dini layetegayyer ahkmndan mlhem olan ve ulhiyetle daimi temas hlinde bulunan kanunlarmzn en kuvvetli messir olduklarna phe edilmemelidir Dinlerin deimeyen hkmler ifade ettiini, esaslarn dinden alan kanunlarn, uyguland toplumlar indiklari ilkel devirlere balayarak iler-lemeye engel olduklarn sylemek yanl mdr?

Dinlerin sadece vicdan ii olarak kalmasn istemek doru deil midir? Yargtay Bakanvekili Osman irin’in “1. Yargtay Bakan Osman Arslan, konuyla ilgili olarak: Gene, 19 Aralk gnl ve sayl R.

Devrimin ideolou olan Bozkurt’un Trk Devrim Tarihi’nde nemli bir yeri vardr. O’nu anmann ayr bir anlam vardr. Bozkurt’u atlayarak Trk Kaaynarca anlayamazsnz. Kimilerine gre o devrimin ‘ideologu’ kimilerine gre ‘bir yanarda’. Bizzat halka da inerek anhlamas da devrimi anlatr. Bu konuma gerekten Kzynarca Devrimini anlatan bir ierik tar. Bozkurt’un fikirlerinin ne kadar salam bir ayaa dayandn grrsnz.

Ben diyebilirim ki Trk olmasaydm kendimi dnyann en baht-sz adam sayardm Vefa duy-gusu nasl erdemli insanlarn bir zellii ve nitelii ise er-demli toplumlarn da vefal olma zorunluluu vardr. Byk devrimci Mahmut Esat Bozkurttan dn alarak szlerimi tamamlamak istiyo-rum.

Hepinizi saygyla selamlyorum “. Veli Deveciolu’nun, Mahmut Esat Bozkurt ‘u ilk nce nerede tandn aklayan konumas, bu byk insann haklarn korunmasyla ilgili konularda ne kadar hassas ve vicdan sahibi kaaynarca gsterdiinden, deinmeden geemiyeceiz. Savcl grevine balamak zere 31 Austos gn amtlamas gittiini akladktan sonraki olaylar yle anlatyor: Baktm kitabn ba tarafnda, Mahmut Esat Bozkurt’un savclara genelgesi var. Nasl he-yecanlandm, baladm okumaya, iinizde bilemiyenleriniz olabilir.

Ben isterseniz ksaca bir tekrar edeyim. Meri kysnda alan Trk kylsnn, kaynacra kaybetmi Trk kylsnn ve bu vatanda en kk bir hakszla maruz olan insalarmzdan, Bingl dalarnn kuytularnda, ssz kuytularnda nafakasn bekleyen k-szlere kadar herkesin herkesin gz yandan siz sorumlu-sunuz! Bingl dalarn ssz kuytularnda yaayan kszlerin gz yalarndan ben sorumluymuum.

Birden aklma geldi ki, kap ak ben de orada savcym. Hemen kalktm, kapy kapattm ve ki-litledim. Biraz sonra kendime gelince gzlerimin yan sildim. Tekrar atm, ite Mahmut Esat Bey’i o byk hukukuyu, o idealist insan, o gerekten herkesin hayranlk duymas gere-ken kaynarxa byk kahraman, ben ite ilk kez byle tan-dm. Aradan krk be yl gibi, bir mr saylabilecek kadar uzun zaman geti. Ama hl o n hi unutamam Mahmut Esat Bozkurt’un Cumhuriyet Savclarna genelgesi, panel tutananda ksmen yanl yer aldndan, dorusu, gene Deveciolu’nun Cumhuriyet gazetesinin 24 Austos gnl saysnda kan bir yaz-snda yazd gibi: Meri kylarnda alan Trk kylsnn kaybolan sapann-dan tutunuz da, bu vatanda yaayanlarn urayaca en ufak bir hakszlktan, hatta Bingl dalarnn ssz kuytularnda bekleyen kszlerin gz yalarndan siz sorumlusunuz”.

Doaldr ki, kaunarca ynetim kadrosunu da. Bylece liderin evresinde kadroyu oluturan yneticiler sayesinde, devrimler oaynarca yaylr ve geni halk kitlelerince zmse-nir. Liderin geni grll ve devrim kadrolarnn anlay ereve-sinde giriilen zverili aba sayesinde halk, devrime balanr. Yaplan kkl reformlar ve getirilen yeni kurumlar halk nezdinde itibar grr. Kaynarcw devrimin gereklemesinde Mustafa Kemal Atatrk’n dehas nde gelir. O’nun sayesindedir ki, asrlardr imparatorlukla ynetilen, padiahn dudaklarndan kan bir ift szle insanlara hk-mettii bu topraklara, Cumhuriyet ynetim ekli olarak yerlemi, “akl dinden, bilim inantan syrlarak” laiklik devlet ynetimince temel ilke olarak benimsenmitir.

Kukusuz laikliin yerlemesi hi de kolay olmamtr.

Kaynarrca ve yakn evresinin bandan beri aklnda olan “laiklik,” ilk anayasada yer alamam, toplumun alma sreci dnlerek bir sre beklenil-mitir. Cumhuriyet’in ilanndan kaynnarca yl sonra yani ylnda Ana-yasa’dan, devletin dini blm karlmtr. Laiklik szcnn Ana-yasa’ya girmesi daha sonralara, ylna denk gelir. Klk kyafetten toplumsal dzene dek laikliin gerekleri toplumca her alanda hissedilmeye balanm ve kk bir aznlk dnda top-lumda geni kabul grmtr.

Cumhuriyet’i kuranlarn en nemsedik-leri konu hukukta laikliin biran nce gereklemesiydi. Cumhuriyet Savclar Meri kylarnda alan Trk kylsnn kaybolan sapanlarndan tutunuzda, bu yurtta yaayanlarn urayacaklar en ufak bir hakszlktan, hatta Bingl dalarnn ssz kuytularnda nafakalarn bekleyen kszlerin gzyalarndan siz sorumlusunuz!

Kadnn tankl geri plandayd. Mirasta erkek bir pay alyorsa, kadn bunun yarsn alabiliyordu.


Erkein boanma hakk vard. Hatta tek szckle “Bool” diyerek bu hakkn kullanyordu. Bunu yapt zaman kimse erkein yakasna yapamyor, bata onca yllk kars olmak zere hi kimse erkee bu hareketinin hesabn soramyordu. Kadn, eriat hukukunun bir gerei olarak bir bana ya babasnn evine dnyordu, ya da keli-menin tam anlamyla ortada kalyordu.

Laikliin toplum nazarnda benimsendiinin en nemli wntlamas, Cumhuriyetle gelen Medeni Yasann kabulyd. Cumhuriyet aydnlan-mas, hukuk devrimi ve nihayet Trk Medeni Yasas denince akla ilkin Atatrk gelir. Peki, kimdi bu Bozkurt?. Cumhuriyetin kurulmasyla birlikte, mecliste milletvekili olur ve fikrinde her zaman var olan hukuk devrimini gerekletirmek iin esiz bir abaya giriir.

Esat Bozkurt adnda gen bir Adalet Bakan temsil eder. Bozkurt bizzat kendisi tarafndan antlajas savunma oaynarca bu davay kazanr. Ve Mustafa Kemal Atatrk tarafndan kendisine bu davada geen ge-minin ad olan Bozkurt, soyad olarak verilir. Bozkurt’un nemli baars kukusuz ki bu kadarla snrl deil-dir.

Yukarda da belirttiimiz gibi er’i hukuk kurallarndan oluturul-mu Mecelle yerine, svire’den alnan Trk Medeni Yasas’nn Trk Hukuk sistemine uydurulmas da onun zverili abalaryla gerekleir. Onun Trk Medeni Yasasnn nszne yazd metin, yalnzca Atatrk devrimlerinin kuramsal zn oluturmaz ayn zamanda laikliin gerekliliini de vurgular.

Hibir uygar ulus byle bir inan evresinde kalmam ve yaamn gereklerine uygun hareketle zaman zaman ken-dini balayan gelenek ve grenekleri ykmakta duraklamamtr.

Trk Medeni Yasas’nn Trkiye Cumhuriyeti’nde uygulama ortam bulamayaca dncesi sakattr. Bu tez, Trk Ulusunun uygarlk yeteneine sahip bulunmadn belirten bir mantk dizisine varlma-syla sonulanabilir.

Kazm Kolcuolu 17 ann tamamen tersidir. Trk yenileme tarihi tank tutularak kqynarca ki, Trk Ulusu yzylmzn gereklerine kayjarca olarak vcuda getirilen kabul edilebilir ve salam ve akl ve zek ile yorulmu yeniliklerden hibirine kar kmamtr. Bu srenin ok ksa olduunu ileri sren ve svire’de bile 4 yllk gei akynarca ngrld-n dine dayal hukuk sisteminin kolay kolay deitirilmeyeceini ne srenlere kar da Trk Hukukularna gvendiini ve bu gven ve inanla alt aylk srenin antlamax olacan bildirmitir.

Medeni yasay srasyla, dier temel yasalar izlemitir. Yusuf Ziya Orta, onun iin svire dalarndan Anadolu dalarna silah omuzda koan hukuk dok-toru diyerek tanmlamakta, ve vatan hududundan fikir hududuna dek her cephede dve dve elinde kalemle yaama veda ettiini vurgu-lamtr. Bozkurt’un zerinde durduu adalk konusunun ne derece nemli olduu gnmzde yaanan kimi olaylardan aka grnmektedir. Bu altn deerindeki satrlar, bugn de geerliliini korur.

Ancak gnmzde Cumhuriyet Aydnlanmasndan rahatsz olan evrelerin homurtularn da duymazlktan gelemeyiz. Aydnlanma dev-rimini gerekletirenler bugnk manzaray grseler ne dnrlerdi acaba? Kadnlarn mecellede ad yoktu.


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The A is complemented by an extensive range of set-top-box middleware, browsers, conditional access and DRM options. The A can decode resolutions up to i 60Hz but is also able to de-interlace content and display it progressively – such as de-interlacing i to p – to deliver the picture quality your customers expect on their high-end LCD and Plasma TVs.

Amino A140 IPTV Set-Top Box

The support of low bitrate advanced video codecs provides operators with the opportunity to grow revenue generating services, while maximising the efficient use of network bandwidth, creating the ability to:. The unique Amino styling sits elegantly with any latest top-specification AV equipment in the living room. The A is supported by an amio ecosystem of middlewarebrowser, conditional access and DRM options required for the widely varying configurations of the IPTV market. The A holds a complete software image in on-board flash memory, and is also designed to support secure bootstrap from a multicast server.

At any time, a deployed A can be upgraded with a new software image via the secure multicast server. The multicast approach ensures that very large numbers of deployed set-top boxes can be upgraded without placing an individual load on the server or the network.

Amino A | Advanced Media Technologies, Inc.

For security, software images can be signed with keys unique to each deployment. Please note the supply of a browser on Amino devices is not covered by any warranty, only the hardware is covered against defects.

Aminp Mod and loop through. Advanced CODEC Support The support of low bitrate advanced video codecs provides operators with the opportunity to grow revenue generating services, while maximising the efficient use of network bandwidth, creating the ability to: Reach a greater number of subscribers Increase the number of interactive and multicast channels Enhance viewing experience with HD channels.

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Mai-marele celor de la rebu 4 lit. actualizqta

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Cui pe cui se? Sa zambesti sau sa te incrunti?


Atal Indore City Transport Services Limited. SUTP PROJECT (under World Bank- GEF). In the context of rapid growth of the city, increasing mobility, high travel. Public transport development (BRTS);; Non-motorized transport development;; Intelligent Transport System (ITS); and; Integrated land use, transport planning. iBus is a mobile application developed to provide convenience to large number of population commuting through iBus system in Indore. This application is an.

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But has this new transport system really paid its people as good as the government expected prior to the launch of its idea.

No wonder the ibuses have really patched a mark to buoy the trait of nascent in the city. No wonder it has allured enough hoi polloi, who refrained from city buses until now, to prefer using them. The low rates of the well equipped buses are another good reason to applaud the new venture by the government, engaging around 70, passengers on its route every day.

But is that all looking good enough from the other side of the road, literally?

Apart from the free moving insore the healthy bus travel, BRTS has lodged Indore citizens with acute congested alleys. Today, traffic jam is the paramount issue of the trending Indore.

With the total investment of a massive, powered by Government of India and the World Bank, all that the rapid transportation could curb is previous city buses on streets, giving rise to the new age of ibuses, but at the same time the millions invested have actually been dumped with the brs of the lane leaving Indore with a utopian notion of the BRTS plan.

This one seeks inspiration from the lanes of Ahmedabad, where the idea proved enough strength due to broad lanes unlike that of Indofe where the unplanned introduction of half way adopted plan has created a bizarre to the mango people.

I-BRTS Service in Indore

Never-the-less, the decision of Justice N. Modi to permit four wheeler vehicles in the BRTS lane, where on one hand has helped to check congestion but on the other has spoiled the plan all the more. With the increasing complaints of the passengers regarding threats from four wheelers on the lane, the idea of free lane seems to bets in vain. Undeterred from all the other sets of chaos that the system has managed to indode up, the introduction of the Urban Transportation Plan has surely lead a lot of employment via the traffic security personnel in the city.

Indore’s new BRTS: Some interesting facts

This could be considered as one of its major turn towards Urbanisation. In lieu of all the issues in the world, BRTS has been the only possible ihdore bringing the two opposition political parties to deem in the same invore. Still hoping to get the plan right and in favour of its contenders, government is looking forward to introduce foot over bridges making it easier for pedestrians while checking on roadside accidents at the same time.

The idea is to promote use of cycles as an alternative to private fuel vehicles, blazing the new Indore rising smart and healthy. The most incore question of Indoreans to be answered by the government is that how the issue wheeling under ibuses would be resolved and if the tax paid by the local hides would ever grant them its reward in the name of rapid transport and yet free lanes.

AiCTSL-City Bus Indore

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CIMZIA is indicated for the treatment of adults with moderately to severely active rheumatoid arthritis; CIMZIA is indicated for the treatment of . drug interactions. o Cimzia is indicated for reducing signs and symptoms of Crohn’s disease and modifying anti-rheumatic drug (DMARD). 3. Cimzia [package insert]. Smyrna. Medscape – Rheumatoid arthritis and Crohn disease dosing for Cimzia ( certolizumab pegol), frequency-based adverse effects, comprehensive interactions.

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Cimzia is mostly used for conditions that are severe, moderately severe or getting worse, or when patients cannot use other treatments. For detailed information on the use of Cimzia in all conditions, see the summary of product characteristics.

Cimzia can only be obtained with a prescription and treatment should only be started by a specialist doctor who has experience in diagnosing and treating the diseases that Cimzia is used to treat.

Cimzia | European Medicines Agency

Cimzia is lackage as pre-filled syringes, prefilled pens and dose-dispenser cartridge. It is given by injection under the skin, usually in the thigh or abdomen tummy. Treatment starts with a mg dose given as two injections, followed by a further mg dose two and four weeks later. After this, depending on the condition pafkage treated, patients should continue with mg or mg, given as one or two injections every two or four weeks. After training, patients may inject Cimzia themselves if their doctor agrees.

A monoclonal antibody is a protein that has been designed to recognise and attach to a specific structure in the body.

Dosing Information

Certolizumab pegol has been designed to attach to a messenger protein in the body called tumour necrosis factor alpha TNF-alpha. This messenger is cimziaa in causing inflammation and is found at high levels in patients with the diseases that Cimzia is used for. By blocking TNF-alpha, certolizumab pegol reduces inflammation and other symptoms of the diseases.

Pegylation decreases the rate at which the substance is removed from the body and allows the medicine to be given less often. Nine cimzla studies involving over 3, patients have found Cimzia effective for reducing symptoms of inflammatory conditions.

The studies included adults with active rheumatoid arthritis, axial spondyloarthritis, psoriatic arthritis and moderate to severe plaque psoriasis:. Similar results were seen cimzzia a study with patients who had not adequately responded to other medicines such as methotrexate. However, the dose of Cimzia used in this study was higher than the usual dose. In patients with active rheumatoid arthritis who had never received Packzge, treatment with Cimzia led to sustained remission no detectable disease activity after 52 weeks of treatment.

A third study compared Cimzia with placebo as well as another medicine called etanercept. The most common side effects with Cimzia affecting up to 1 in 10 people are bacterial infections including abscesses cavities containing pusviral infections including herpes, papillomavirus and influenzaeosinophilic disorders disorders of eosinophils, a type of white blood cellleucopenia low white blood cell countsnausea feeling sickheadaches including packaggesensory abnormalities such as numbness, tingling and burning sensationhigh blood pressure, hepatitis liver inflammation including increased levels of liver enzymes, rash, fever, pain, weakness, itching and reactions at the injection site.

For the full ppackage of side effects of Cimzia, see the package leaflet. Cimzia must not be used in patients with active tuberculosis, other severe infections, or moderate to severe heart failure inability of the heart to pump enough blood around the body.

For the full list of restrictions, see the package leaflet. Recommendations and precautions to be followed by healthcare professionals and patients for the safe and effective use of Cimzia have been included in the summary of product characteristics and the package leaflet.

As for packags medicines, data on the use of Cimzia are continuously monitored.

Side effects reported with Cimzia are carefully evaluated and any necessary action taken to protect patients. More detail is available in the summary of product characteristics. Cimzia has been shown to reduce the rate of progression of joint damage as measured by X ray and to improve physical function, when given in combination with MTX.

Cimzia is indicated for the treatment of adult patients with severe active axial spondyloarthritis, comprising:. Adults with severe active ankylosing spondylitis who have had an inadequate response to, or are intolerant to nonsteroidal anti-inflammatory drugs NSAIDs.

Cimzia, in combination with MTX, is indicated for the treatment of active psoriatic arthritis in adults when the response to previous DMARD therapy has been inadequate. Cimzia can be given as monotherapy in case of intolerance to methotrexate or when continued treatment with methotrexate is inappropriate.

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Veterinary regulatory Overview Research and development Marketing authorisation Post-authorisation. Table of contents Overview Authorisation details Product information Assessment history. An overview of Cimzia and why it is authorised in the EU Cimzia is a medicine that is used in adults to treat the following diseases: Cimzia contains the active substance certolizumab pegol.

Expand all Collapse all. For more information see the package leaflet or contact your doctor or pharmacist. The studies included adults with active rheumatoid arthritis, axial spondyloarthritis, psoriatic arthritis and moderate to severe plaque psoriasis: For active rheumatoid arthritis that had not improved adequately with disease-modifying antirheumatic drug DMARD treatment, two main studies found Cimzia effective when used with methotrexate when compared with placebo dummy treatment.

Also, X-rays showed that joint damage worsened to a lesser extent in patients who received Cimzia. In the treatment of moderate to severe plaque psoriasis, Cimzia was compared with placebo in two main studies. Treatment with Cimzia mg every two weeks in the two studies led to Patients on Cimzia mg every two weeks led to Cimzia received a marketing authorisation valid throughout the EU on 1 October Product details Name Cimzia. You are therefore advised to be selective about which sections or pages you wish to print.

Rheumatoid arthritis Cimzia, in combination with methotrexate MTXis indicated for: Axial spondyloarthritis Cimzia is indicated for the treatment of adult patients with severe active axial spondyloarthritis, comprising: Ankylosing spondylitis AS Adults with severe active ankylosing spondylitis who have had an inadequate response to, or are intolerant to nonsteroidal anti-inflammatory drugs NSAIDs. Psoriatic arthritis Cimzia, in combination with MTX, is indicated for the treatment of active psoriatic arthritis in adults when the response to previous DMARD therapy has been inadequate.

Changes since initial authorisation of medicine List item. Initial marketing-authorisation documents List item.

How useful was this page? Leave this field blank. International non-proprietary name INN or common name. Anatomical therapeutic chemical ATC code.

Date of issue of marketing authorisation valid throughout the European Union.


Re: CDM B 16×2 LCD pin diagram required. Helpful web site. finally i got the datasheet as mail from Crystalonic itself. CDM B. 16*2 LCD (Liquid Crystal Display) module widely used in devices & circuits. This tutorial covers pin diagram, description and Datasheet of 16×2 Character LCD. Course Work: a) General: Intel MCS51 Family Microcontroller: http://datasheets. Ċ, CDM B

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Essentials Only Full Version. My LCD code is not working But i didnt get anything on Display. Please kindly reply me,here is my code. Hi, In your lcd init code. I’m assuming this is the common hitachi type lcd 16×2 display.

Character LCD Display 16×1

You always have to initialise in 8 bit mode first before you can set 4 bit mode. The details are in the data sheet but it goes like this 1. Power on-wait 15msec 2. This is just what it says in my datasheet. I am sure that all these types of displays need to be initialised in 8 bit first though. Thanks for the response. I dont have the data sheet for my LCD. If you have please dtaasheet to me. I used 28h,it is for 5×7. The time you spent typing the request is more than enough to get it after a simple search through Google.

CDM B 16×2 LCD pin diagram required

He meant a Hitachi type – hitachi compatible, hitachi standard etc. The controller on the display is the hitachi standard type. I started the 4 bit mode at beginning itself. The LCD needs initialization before it enters the 4-bit mode. Refer the flowchart in attached file.

However you must have that information as you have the values for a clear display, and all dtasheet other commands. In the attachment debrajdeb supplied it shows exactly the sequence you must run to initialise. You will notice that a substantial delay is needed after power on.

You haven’t even called your 2. BUT that is still too short anyway. You must allow a 15ms delay at the start of lcd init. So go back and create some extra delay routines.

Make xdm16216b present delay routine for 5 ms. Creat a 15 msec routine by calling delay5 three times. And also create a usec delay routine to be used between executing all other commands.

If it still deosn’t work after you try this I don’t vdm16216b I can be of any further help. Please, regardless of how you got it to work in 8 bit mode follow exactly this sequence.

Once you have it working you can try altering and see what it will tolerate before becoming unstable.

What are good practices when using SPI? Debug breakpoints automatically disabled Future of PIC32 16F88 cannot set internal oscillator frequency beyond Why does my PIC32 run slower than expected?

Buenos Aires – Argentina Status: In practice, however, there is. America’s finest city Status: The controller on the display is the hitachi standard type 7th dan instrumentation and controls 5.

Attached Image s 7. Guest Super Member Total Posts:


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Search the history of over billion web pages on the Internet. August, 2nd Edition: They carry a distinctive flavour of the Northeast and its people who stay burbi to nature in these areas. Tales like The Sly Fox is indeed well translated and edited. My best wishes for your efforts. Abdul Kal am Ms. Just like language as a means of expres- sion sprouted up from the roots of national life, folklore has also been a form of revelation and characterisation of national life since the ancient past.

All the people, the learned and the laity, the elite and the commons comprising a nation leave their imprints on their language. Similarly, all classes of people in a nation leave an indelible mark of age-old practice and usage, habits and customs as also of thought and imagination in the folk-tales. Therefore, just as philology and mythology are the pre-requi- sites necessary to trace out the unwritten history of the national aairr of man, folk-lore is also equally essential for the purpose.

Burhi aair sadhu (eBook) eBook |

Bopp, the renowned German philologist asserted that the Teutons, the Buhi, the Hindus and all other Aryan races were originally the same, that their roots lay in the same family of the Central Asia and that they are the branches of a single tree. This theory has since been confirmed by analy- sis and comparison of the themes contained in the folk-tales.

Till a long time ago, people considered folk-tales to be childish and trifling as they didnot know their intrinsic value. But budhi German schol- ars were the first to contradict this wrong concept.

Initially, the true value of folk-tales burji determined in Germany and the tales were studied in a scientific manner. But this endeavour bore mature fruits only after the great effort of the famous scholar Grimm during the period starting from to A. The folk-tales gained currency among the people through oral transmission from one generation to another.

But the scholars collected them for record from the old women in Germany who used to work as paid weavers. In reality, it was due to the efforts of the German scholars that the modern civilized world has been made aware of the fact that, the basis of the birhi of a nation and the origin of a word in a language are more valuable than the history of a great war.

The other burhj comprises the tales which are an outcome of wild imagination for providing amusement to the young and the old alike — especially the children. But, whatever might be the purpose behind the origin of folk-tales, scholars have now been able to extract the essence of ancient history of the human race from them which has enriched the sphere of human knowledge. The aim of this preface however is not to discuss the matter any further within its narrow ambit.

The sahdu may observe that the central theme in this book are to be found in the tales of other provinces of India, especially those sadyu Bengal. But it would be wrong to assume burho these are com- posed after the model of tales of other provinces. There are many reasons behind the similarity of folk-tales of one province or country with those of another.

Among them, the first is that the tales were composed during the time when the ancient Aryans lived together. In the course of time, as the Aryans migrated to different parts of Europe and Asia, there were changes in their nature and disposition conforming to the changed envi- ronment, situation and circumstances.

Similarly, changes have also taken place in the folk-tales. But the basic structure of the tales has not changed nor will change.

As such, even though the outer form of the numerous Indo-European folk-tales might be different, the foundation remained the same. Therefore, when the tales told by the nurses in India while comforting children resemble those told by the German, the Norwegian and the French nurses, one finds no basic difference in them except in matters of lan- guage and set-up.

Again, sometimes it is seen that folk-tales of a country get orally migrated to some other country. Some outer changes are inevitable in them during this process. As a result of wide circulation for a consider- able time in a neighbouring country, a tale loses its original form and adopts a local texture. But such tales are few in number. It is also natural for the local folk-tales to find an easy access into a neighbouring country.

As such, we find many Asamese folk-tales prevalent in North Bengal. It will be pertinent to keep in mind that since certain parts of East and North Bengal were included in the ancient kingdom of Kamrupa, many of Assamese folk-tales have become a part of Bengali folklore.

Now-a-days we find Bengali writers publishing folk-tales as “Rupkatha”. If we care- fully observe the writings, it will be clearly seen that the influence of Assamese folk-tales is traceable more in the books of the writers from North- Bengal than in those of the writers of West Bengal.

This can be proved by reference to two books on folktales viz. There is another reason behind the similarity among sadju of different countries.

Full text of “GRANDMA’S TALES”

It is termed as co-incidental similarity. All human- beings in a way are the same everywhere. The mode of thinking on various aspects is the same among them. As such, even certain tales of the Hottentots or of the Zulus have similarity with those of the Aryans.

The Assamese are aware of the value of folk-tales since the ancient past and they have always held them in high esteem. Thus it can be easily understood that in Assam these gratifying tales were narrated by the wise to the common masses and to their chil- dren.

No nation of any other country has given such tales or stories a name as glorifying as this. Language and folk-tales are the bone and marrow of a nation.

Aari, I would like to mention that we received many tales incor- porated in this book from the persons mentioned below. But, it burrhi not feasible for is to point out which tale was contributed by whom. It is because we received indentical tales written in different styles of compo- sition from several persons. The tales were compared, made additions and alterations in them and then selected after careful perusal.

In reality, it may be mentioned that the language in which they wrote the tales to us is literally not there. One may incidentally come across an original sen- tence or two in certain tales. Some of the tales of course are completely ours. Be it whatever it is, zadhu are grateful to them for their help.

Translation of such a book is a challenging task and I must say that Pallavi has attained an im- pressive measure of success in her undertaking.

Grandma’s Tales (Burhi Aair Sadhu)

The need of introducing this sachu of Assamese folklore to the lovers of culture and literature, who are not familiar with the Assamese language was very much there, and as such, she has filled up a long-standing necessity. The very act of selecting “Burhi-aair Sadhu” for translation into English is a commendable sair.

The translator is a very young college-student and her keen interest in Assamese literature deserves wide appreciation. I expect that she would pursue this task during the years to come through more aaif translations. True, the young translator has some shortcomings, but I am sure of the fact that she would overcome those shortcomings. My bhrhi best wishes to Pallavi. This language has since been made the official language of the state of Assam, the heart-land of the North-East. Inspite of such literary tradition, the language is little known to the rest of the world.

This is due to factors like geographical burbi, communication bottle-neck and lack budhi ex- posure. Through the medium of the international language English, I have made a humble effort to bring out some folk-tales of this regional language to a greater number of readers. These folk-tales, though basi- cally meant for children, form an integral part of the Assamese folklore. The stories are not to be taken to be literal translation of the original because some adaptations had to be made to fit into a foreign language.

The meanings of the Assamese words which had to be retained even in the course of the translation have been given at the end of those stories where required. I am indebted to my mother Smt. Juna Barua, and my father Dr. Siva Prosad Barua, who have always stood by me in all my endeavours. I would also like to thank buurhi sister Pranami, whose sheer enthusiasm about my work has been a source of encouragement for me. I express my deep sense of gratitude to Mr. Lec- turer of English in the Tezpur College for consenting to undertake the strenuous task of proof-reading and taking all pains to correct the errors in composition made by me.

I express my heart-felt thanks to Mr.

Pradeep Terang, an experienced artist, for his wonderful illustrations. Before concluding my words, I express my sincere regards to emminent literateur Prof. Hirendra Nath Dutta, for looking into the script of the book and adoring it with a “Foreword” Note. When this is brought out in the form of an art, then it is converted to real pictures. The time and events happening around us is used as a symbol for this purpose.

I have tried to create different characters present in the tales using different colours and cos- tumes. I sincerely hope that the illustrations would make this book more interesting for it’s young readers.

I would like to thank Pallavi Barua, the translator of this Classic, for making me a part of her project, and for providing necessary guidance and suggestion in making the book more lively. Guwahati, Illustrator 8th November, Pradeep Terang Guwahati -15 th November, The monkey and the fox 3. The raven and the sparrow 5. A lady-gardener and a flowering plant 6. The sly fox 7.

The tiger and the crab 8. The old couple and the jackals The long-legged visitor The son bom late The tale of a singora-fish A strong man